These are databases or dictionaries organized around individual people, covering Britain in the long eighteenth century.
BBTI: British Book Trade Index, covering people working in this sector up to 1851.
BIFMO: British and Irish furniture makers from the beginning of the 16th century to the onset of the Great War (1914).
British artists’ suppliers: Courtesy of the National Portrait Gallery, covering the arts supply trades, 1650 to 1950.
British picture framemakers: Courtesy of the National Portrait Gallery, covering picture frame makers, 1600 to 1950.
British picture restorers: Again via the N.P.G., covering 1600 to 1950.
CCEd: Clergy of the Church of England, 1540 to 1835.
FreeReg: Free and open transcriptions of parish registers and related material, 1538 to 1837.
Digital Panopticon: Tracing London Convicts in Britain & Australia, 1780 to 1925.
History of Parliament Online: Biographies of MPs from 1386 to 1832.
Legacies of British Slavery: Excellent resource, detailing the British slave-owners paid ‘compensation’ for the emancipation of the enslaved after 1833.
Munk’s Roll: of the fellows of the Royal College of Physicians. Vol. 2. covers the eighteenth century.
Runaways: Nearly 900 runaways from slavery in Britain, through the advertisements taken out by slaveowners, 1700 to 1780.
Sculptors in Britain, 1660-1851: Via the Henry Moore Foundation.
Smuggling Prosecutions: People prosecuted for smuggling, 1722 to 1732,
Switching the Lens: Records of circa 2,600 black, African and Asian lives in London, 1561 to 1840.
Additionally, there are a number of biographical dictionaries published in the nineteenth or early twentieth century, now out of copyright and so freely available. So far, I have found just the one that covers the eighteenth century and is not duplicated by a modern database:
Plomer, A dictionary of the printers and booksellers who were at work in England, Scotland and Ireland from 1668 to 1725. Archive.org.
Finally, Wikipedia has many extensive and multiplying categories for Eighteenth Century English People and Eighteenth century English People by Occupation.